Home Pharmaceutic PVP Povidone(PVP)
Product Name:Polyvinylpyrrolidone
Chemical Description:Homopolymer of 1-Vinly-2-Pyrrolidone,Polyvinylpyrrolidone,PVP
INCI/CTFA:PVP
Pharmacopeia Name:Povidone(Povidonum)
CAS NO.:9003-39-8
Product Properties: Povidone is a hygroscopic polymer ,supplied in white to creamy white powder or flakes,ranging from low to high viscosity & low to high molecular weight,which characterized by K Value.It’s easily soluble in water and many other organic solvents,with excellent hygroscopisty,film-forming,adhesive,chemical stability and toxicological safeness characters.
Applications:Povidone is one of the most important excipients in the worldwide for pharmaceutical industry,whatever for human health care products and animal health care products.Which used as:1)Binder for tables,capsule,2)Sugar coatings and films,3)Thickening agent,4)Solubility Improver for poorly soluble drugs,5)Bioavailability Enhancer for drug’s active ingredients,6)Pore-forming for membrane products.
Specifications:
Product |
Povidone K15 |
Povidone K17 |
Povidone K25 |
Povidone K30 |
Povidone K60 |
Povidone K90 |
|
Appearance |
White or yellowish-white,hygroscopic powder or flakes |
||||||
Solubility |
Freely soluble in water,in ethano(96%) and in methanol,very slightly soluble in acetone. |
||||||
Appearance of Solution |
Clearly and not moren intensely coloured than reference solution B6,BY6 or R6 |
||||||
Identifications |
Meet ID Tests |
||||||
pH Value(5% in aqueous solution) |
3.0-5.0 |
3.0-5.0 |
3.0-5.0 |
3.0-5.0 |
4.0-7.0 |
4.0-7.0 |
|
Viscosity(Expressed as K Value) |
12.75-17.25 |
15.3-18.36 |
22.5-27.0 |
27.0-32.4 |
54.0-64.8 |
81.0-97.2 |
|
Adehydes(Expressed as Acetaldehyde) |
500 ppm max. |
500 ppm max. |
500 ppm max. |
500 ppm max. |
500 ppm max. |
500 ppm max. |
|
Peroxides(Expressed as H2O2) |
400ppm max. |
400 ppm max |
400 ppm max |
400 ppm max |
400 ppm max |
400 ppm max |
|
Formic Acid |
0.5% max. |
0.5% max. |
0.5% max. |
0.5% max. |
0.5% max. |
0.5% max. |
|
Hydrazine |
1ppm max. |
1ppm max. |
1ppm max. |
1ppm max. |
1ppm max. |
1ppm max. |
|
N-Vinylpyrrolidone(Impurity A) |
USP26 |
1000 ppm max. |
1000 ppm max. |
1000 ppm max. |
1000 ppm max. |
1000 ppm max. |
1000 ppm max. |
Current USP/EP/BP |
10 ppm max. |
10 ppm max. |
10 ppm max. |
10 ppm max. |
10 ppm max. |
10 ppm max. |
|
2-Pyrrolidone(Impurity B) |
3.0% max. |
3.0% max. |
3.0% max. |
3.0% max. |
3.0% max. |
3.0% max. |
|
Heavy Metals(as Pb) |
10 ppm max. |
10 ppm max. |
10 ppm max. |
10 ppm max. |
10 ppm max. |
10 ppm max. |
|
Water |
5.0% max. |
5.0% max. |
5.0% max. |
5.0% max. |
5.0% max. |
5.0% max. |
|
Sulphated Ash |
0.1% max. |
0.1% max. |
0.1% max. |
0.1% max. |
0.1% max. |
0.1% max. |
|
Nitrogen Content |
11.5-12.8% |
11.5-12.8% |
11.5-12.8% |
11.5-12.8% |
11.5-12.8% |
11.5-12.8% |
Name: Mr. He John
Mobile:+86 18765995738
Tel:+86 18765995738
Whatsapp:8618765995738
Email:seabond@hbdchem.com
Add:Rm327(A), NO 43, Beijing Road, Free Trade Zone, Qingdao, China